Mary M. Tomayko, MD, PhD

Associate Professor of Dermatology

Departments & Organizations

Dermatology: Tomayko Lab | Yale Dermatology Associates

Faculty Research

Yale Cancer Center: Cancer Immunology

Yale Medicine

Office of Cooperative Research


Mary Tomayko M.D., Ph.D., is a physician scientist who brings insight from her immunology research to her medical dermatology practice. Dr. Tomayko is an attending physician at Yale-New Haven Hospital, Yale Dermatology Associates, Yale Health and the Yale Primary Care Center, where she directs adult dermatology. Upon consultation requests from colleagues, Dr. Tomayko evaluates individuals with complex dermatologic conditions, including autoimmune and inflammatory disorders, skin cancer and genetic disease. She employs a range of treatment modalities, including systemic immunomodulators, targeted “biologic” agents and phototherapy and performs surgical excisions of skin cancers and skin lesions. Dr. Tomayko directs a monthly Immunobullous Clinic, which cares for patients with B cell-mediated blistering skin disease.

Dr. Tomayko’s research laboratory has 2 intertwined missions. The first is to undercover the underlying mechanism of immune dysregulation in bullous pemphigoid, in order to develop targeted, effective and safer treatments for this autoimmune blistering disease. The second is to understand how long-lasting immunity, “memory”, is established and maintained. In seminal work, she has uncovered unexpected diversity in phenotype and function of the cells that maintain B lymphocyte immunity and has identified novel molecular pathways essential for lasting immunity. This work, funded by the National Institute of Health, suggests exciting new approaches to enhance and suppress immunity therapeutically. Dr. Tomayko publishes peer-reviewed articles and chapters and regularly presents her work at national and international meetings. She is a reviewer for scientific and medical journals and foundations. She is a Medical Editor for Dermatology Focus, a publication that highlights recent advances in the field.

Dr. Tomayko is a director of dermatology education at Yale University School of Medicine. She mentors undergraduate, graduate and medical students in her laboratory, and trains resident physicians and fellows.

Education & Training

MD Univ. of Pennsylvania School of Medicine (2000)
PhD Univ. of Pennsylvania School of Medicine (1998)
Postdoctoral Fellow Yale University School of Medicine
Resident Yale Unversity School of Medicine
Intern University of Pennsylvania Hospital
Board Certification AB of Dermatology, Dermatology (2005)

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Contact Info

Mary M. Tomayko, MD, PhD
Patient Care Locations
Primary Care Center (PCC)840 Howard Avenue
New Haven, CT 06519
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Yale Health Center
55 Lock Street, Ste 3rd Floor

New Haven, CT 06511
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Mailing Address
PO Box 208059
333 Cedar Street

New Haven, CT 06520-8059

Curriculum Vitae