Yale School of Medicine

Dermatology, Yale School of Medicine

Dermatology, Yale School of Medicine

Dermatology
333 Cedar Street, LCI 501
PO Box 208059
New Haven, CT 06520-8059
Tel: 203.785.4091
Fax: 203.785.7637

Current Clinical Trials

Transimmunization for non-small cell lung cancer

A clinical trial of Transimmunization for the treatment of solid cell tumors in stage IIIB or greater non-small cell lung cancer (NSCLC) is currently underway at Yale.  Information about this trial is listed below.

  For more information, please call the
  Yale Cancer Center Clinical Trials Office at
  203-785-5702.

Transimmunization was developed after years of laboratory research advanced the understanding of the underlying principles of ECP (Extracorporeal photochemotherapy or photopheresis).  The scientific basis of ECP is the ability to stimulate the development of powerful stimulators of the immune system called dendritic cells.  Transimmunization is a more efficient means by which to bring these dendritic cells in contact with target cancer cells, before they are retuned to the body to stimulate an anti-tumor immune response.

HIC Number

26573

Full Title

Phase I Feasibility Study: Combined Modality Treatment with Transimmunization for Non-Small Cell Lung Cancer

Trial Type

Therapeutic

Disease

Phase I

PI

Lynn Wilson

Primary Objective

To assess the safety of utilizing Transimmunization as a component of combined modality treatment of stage IIIB or greater non-small cell lung cancer (NSCLC).

Target Population

Histologically confirmed non-small cell lung cancer; Staging by CT scan of chest, abdomen and MRI of brain; Willing and able to undergo two lung biopsy procedures by bronchoscopy.

Exclusion

History of, or active infection with, human immunodeficiency virus (HIV), hepatitis B, or hepatitis C; History of allergic reactions attributed to compounds of similar composition to 8 methoxypsoralen.

FDA Phase

I

 

Research Studies at Yale

At Yale, there are hundreds of clinical research studies underway for a wide variety of conditions. There are also many trials that need healthy volunteers. Learn more...